CapnoSET Mainstream EtCO₂ Technology

Overview

Fast, Reliable, and Cost-EffectiveCapnoSET® mainstream EtCO₂ technology is designed for ease of use, low operational cost, and high reliability across diverse clinical environments including surgical monitoring, ICU, emergency care, and both in-hospital and out-of-hospital transport scenarios.A key feature of this technology is its true plug-and-play functionality, enabled by zero warm- up time. This rapid response capability is achieved through integrated sample gas pretreatment and adaptive compensation, allowing immediate and accurate EtCO₂ measurement upon connection.Extensively validated in clinical practice, CapnoSET® meets the critical demands of time- sensitive care while minimizing setup errors and enhancing treatment efficiency.

Key advantages

CapnoSET® Optical Path Control Technology - Precision Under Variable Conditions

In mainstream EtCO₂ measurement, exhaled breath-saturated with water vapor can lead to condensation within the measurement chamber when ambient temperatures are lower than body temperature. This condensation may cause water droplets to form on internal surfaces, resulting in infrared light scattering and potential overestimation of EtCO₂ concentrations.CapnoSET® addresses this challenge through an advanced optical path control design, which adjusts the incidence angle of the infrared light. This minimizes internal scattering and ensures accurate measurement, even under fluctuating environmental conditions.For sidestream EtCO₂ systems, where condensate accumulation can degrade sampling line performance and risk equipment damage, the integrated TiniStream® technology filters out moisture from the sampled gas. This not only enhances measurement accuracy and response time but also significantly extends the sampling line's operational lifespan.

CapnoSET® Drift Suppression Technology - Stable Precision from Start-Up

During the initial phase of mainstream EtCO₂ monitoring, rapid changes in internal conditions, such as temperature fluctuations, IR source radiation variation, and detector sensitivity shifts can lead to signal drift and compromised accuracy.CapnoSET® incorporates advanced drift suppression algorithms that compensate for both environmental and electrical variations in real time. This ensures full measurement precision from power-on, eliminating the need for extended warm-up periods. The result is consistent, reliable EtCO₂ monitoring with high clinical value, particularly in time-critical and mobile care environments.

Central Monitor Systems

Central Monitoring System - Integrated, Intelligent, and Scalable

The Central Monitoring System is designed around a distributed architecture that enables seamless, real-time access to patient monitoring data across various clinical environments. Comprising a data management center, central station, viewing terminals, mobile access points, and standardized data interfaces, the system supports flexible deployment to meet the needs of different departments and hospital sizes—serving as a foundational layer for full hospital digitalization.

Real-Time Insight, Anywhere Access

With configurable data permissions and real-time data transmission, the system simplifies workflows while enhancing the efficiency and safety of continuous patient monitoring—whether at bedside, on the move, or from centralized locations.

Modular and Scalable Networking

The system’s distributed design allows for customized network configurations tailored to clinical requirements. This flexibility ensures optimal integration of patient monitoring services, supporting both current operational demands and future scalability.

Data-Driven Research Support

Built on proprietary core technologies, the platform provides original, phase-accurate physiological data—ensuring high integrity for clinical research and supporting innovation in medical device development.

Interoperability and Data Security

Equipped with multiple standard data protocol interfaces, the system integrates smoothly with hospital information systems (HIS), streamlining clinical workflows and supporting diagnostic accuracy while maintaining strict data security standards.

Collaborative R&D

ZUG was founded by leading experts in the field of physiological monitoring and life support, our organization is committed to advancing innovation in clinical care. Guided by a team of senior scientists, we integrate deep clinical insight with proprietary core technologies to deliver high- impact solutions across surgical, emergency, critical care, and research settings.

Products & Solutions

We offer a comprehensive portfolio of patient monitoring technologies designed to meet the demands of various medical environments. Our systems are engineered for seamless integration, clinical precision, and operational efficiency supporting care delivery from acute interventions to longitudinal monitoring.

Innovation & R&D

Our research and development efforts focus on both foundational science and practical applications. With a strong emphasis on clinical validation and multidisciplinary collaboration, we continuously deliver advanced technologies that enhance diagnostic accuracy, patient safety, and healthcare outcomes.We actively engage in strategic partnerships with clinical institutions and technology developers to accelerate innovation. These collaborative efforts have led to the co-creation and deployment of specialized monitoring platforms, expanding the reach and relevance of our technologies in real-world clinical practice.

Case Studies

Case 1: ECG-Guided PICC Placement

Electrocardiogram (ECG) guidance enhances the precision of peripherally inserted central catheter (PICC) procedures. By monitoring the progression of the P wave during catheter advancement:

• Increasing P wave amplitude indicates entry into the superior vena cava (SVC).• The maximum amplitude marks optimal tip placement.• Biphasic P waves signal atrial entry, requiring slight retraction for correct positioning.

This method improves first-attempt success rates and reduces procedural risk.

Case 2: External Counterpulsation and Pulse Volume Feedback

OverviewExternal counterpulsation (ECP) is a non-invasive therapy that reduces systolic and enhances diastolic aortic pressure to improve cardiac output and organ perfusion. By increasing diastolic pressure, it enhances coronary artery blood flow, supports ischemic myocardium, and improves cardiac function.

Technology AdvancementAn ECG-triggered pulse volume feedback mechanism has been developed to accurately synchronize counterpulsation with the cardiac cycle. This system provides real-time feedback on therapy effectiveness and helps optimize treatment timing. Ongoing research aims to refine therapy protocols and validate long-term clinical benefits.

Case 3: Peripheral Arterial Oxygen Saturation Mapping

Oxygen saturation monitoring is continuous, non-invasive, and rapid—making it a vital tool in clinical care. However, studies have shown that oxygen saturation levels may vary across different body sites and times, or due to pathological conditions. Mapping peripheral arterial oxygen saturation distribution is therefore essential to advancing precision medicine.

To support this goal, a peripheral arterial oxygen saturation mapping device was jointly developed in collaboration with clinical experts and technology partners. For scientific rigor, the system employs a zero-phase difference design between systemic oxygen saturation and blood perfusion signals, with precise ECG waveform alignment and sampling. Multi-modal analysis techniques are used to extract more accurate and clinically valuable diagnostic insights.